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Mounjaro FAQs

How does Mounjaro help you loose weight?

Mounjaro promotes weight loss by decreasing appetite, as well as directly impacting the pathways that lead to fat loss. Unlike other GLP-1 medications, Mounjaro activates both GLP-1 and GIP receptors, promoting the utilisation of stored fat for energy in addition to curbing appetite.

Mounjaro employs a multifaceted approach to enhance weight management. It facilitates the release of insulin in response to elevated blood sugar levels, aids in the removal of excess sugar from the bloodstream, curtails the liver's production and release of excessive sugar, reduces overall food intake, and moderates the speed at which food exits the stomach. Notably, the latter effect gradually diminishes over time.

 

How effective is Mounajro?

In recent studies (SURMOUNT 1), individuals taking Mounjaro experienced significant weight loss compared with the placebo group.
At 72 weeks the average weight loss was 13.8kg on the 5-mg dose, 19.8kg on the 10-mg dose, and 21.2kg on the 15-mg dose. This equated to an average baseline reduction of 16.0% on the 5mg-dose, 21.4% on the 10mg-dose and 22.5% on the 15mg-dose.

 

How do I use Mounjaro?

Take Mounjaro once a week, selecting a day that suits your schedule. Administer Mounjaro at any time on your chosen day. However, if you wish to change your dosing day, ensure a minimum of 3 days (72 hours) between doses. If a dose is missed, take it within 4 days (96 hours) after the missed dose. If more than 4 days have elapsed, skip the missed dose and resume on your regular day. Avoid taking two doses within 3 days of each other. Consider setting a reminder on your phone for your Mounjaro day, and if you change the day, update your reminder accordingly.

 

Administer Mounjaro by subcutaneous injection, either in your stomach (abdomen), thigh, or upper arm, once a week at any time of the day. Change your injection site each week. You may use the same area of your body, but be sure to choose a different injection site in that area.  Always use a new pen needle for each injection to help prevent infections and blocked needles. In case of an overdose, promptly contact your healthcare provider or seek medical advice.

 

What are the possible side effects of taking Mounjaro?

As is the case with any medication, Mounjaro can cause some patients to experience side effects. Some of these are listed below but for the full list please click here for a copy of the patient information leaflet

Very common and common side effects:

  • Nausea and/or vomiting
  • Gastrointestinal side effects – e.g. diarrhoea, constipation, bloating, indigestion, burping, gas, reflux (heartburn)
  • Symptoms of low blood sugar levels (hypoglycaemia) – these can include but are not limited to sweating, dizziness, feeling light headed, headache, feeling drowsy, feeling weak, confusion, mood changes such as feeling irritable
  • Allergic reactions (hypersisitivity) – e.g. rash, itching, eczema
  • Abdominal pain
  • Hair loss
  • Tiredness
  • Fast pulse
  • Injection site reactions – e.g. itching, redness, swelling
  • Increased levels of pancreatic enzymes – e.g. lipase and amylase

Uncommon side effects:

  • Gallstones
  • Gallbladder infection
  • Injection site pain
  • Increased blood levels of calcitonin

Serious side effects:

  • Inflammed pancreas (acute pancreatitis)
  • Severe allergic reactions (Anaphylaxis)